Cerebrotendinous Xanthomatosis represents a rare and underdiagnosed inherited neurometabolic disorder due to homozygous or compound heterozygous variants involving the CYP27A1 gene.This bile acid metabolism disorder represents a key potentially treatable neurogenetic condition due to the wide spectrum of neurological presentations in which 92-95 ci
Experimental study on the synchronization mechanism and trigger characteristic density of vertical evacuation in crowds
Abstract Due to simultaneous horizontal and vertical displacement during vertical evacuation, the consequences of stampede congestion accidents can be more severe.Generally, pedestrians trigger a synchronization mechanism at some point during the vertical evacuation process.This synchronization behavior helps prevent stampede congestion and improve
Ensuring the Reliability of Functioning of Non-Addressed Fire Alarm
One of the ways that is aimed at reducing losses from fires is to detect a fire at the initial stage of its occurrence, which can be most effectively carried out only with the help of fire automation systems.The latter includes information and measurement systems (IMS) of fire alarm systems, which are part of the fire detectors.Fire alarms (FA) are
Comparing BOLD and VASO-CBV population receptive field estimates in human visual cortex
Vascular Space Occupancy (VASO) is an alternative fMRI approach based on changes in Cerebral Blood Volume (CBV).VASO-CBV fMRI can provide higher spatial specificity than the blood oxygenation level-dependent (BOLD) method because the CBV response is thought to be limited to smaller vessels.To investigate how this technique compares to BOLD fMRI for